小鼠

Casp8 - caspase 8

Alias:
MACH
Mch5
FLICE
CASP-8
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
这个基因是半胱氨酸天冬氨酸蛋白酶家族的一部分,这个家族的天冬氨酸特异性的半胱氨酸蛋白酶在免疫和凋亡信号传导方面研究得相当充分。这个蛋白质是凋亡细胞死亡的开始,由死亡诱导的肿瘤坏死家族受体激活,并针对下游效应子。在小鼠中,这个基因的缺陷会导致胚胎致死。这个蛋白质可能在胚胎发生中发挥作用。可变剪接产生了多种转录变异体,它们编码不同的蛋白质异构体。[由RefSeq,2013年4月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
5
9
52265 bp
55.36
32
30

Casp8 Genetics information (+)

GRCm39

Sequence Homology

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Sequence
Comparison
Al agent
Tutorials
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