人类

CCR8 - C-C Motif Chemokine Receptor 8

Alias:
CY6
TER1
CCR-8
CKRL1
CDw198
CMKBR8
GPRCY6
CMKBRL2
CC-CKR-8
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码β趋化因子受体家族的一员,预测是一个类似于G蛋白偶联受体的七跨膜蛋白。趋化因子及其受体对于各种细胞迁移到炎症部位非常重要。这个受体蛋白在胸腺中优先表达。已经识别出I-309、胸腺激活调节细胞因子(TARC)和巨噬细胞炎性蛋白-1β(MIP-1β)作为这个受体的配体。这个受体及其配体的研究提示其在调节单核细胞趋化作用和胸腺细胞凋亡中发挥作用。更具体地说,这个受体可能有助于激活T细胞在抗原挑战部位和淋巴组织特化区域中的正确定位。这个基因位于趋化因子受体基因簇区域。[由RefSeq,2008年7月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
1
2
3972 bp
40.84
12
--
9
11

CCR8 Genetics information (+)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Mutation Direct
Sequence
Comparison
Al agent
Tutorials
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