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中文小鼠
Casp2 - caspase 2
Alias:
ICH-1
Nedd2
CASP-2
NEDD-2
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这个基因编码一个进化上非常古老且保守的半胱氨酸蛋白酶成员，它在应激诱导的凋亡、DNA修复和肿瘤抑制中扮演重要角色。缺乏编码的蛋白质的小鼠可以正常发育，但显示细胞类型特异性的凋亡缺陷。来自这种小鼠的生殖细胞和卵母细胞在处理化疗药物后对细胞死亡具有抵抗力。[RefSeq,2015年4月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
Casp2 Genetics information (+)
GRCm39
Sequence Homology
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
References Literature
Title
PMID
Journal
Year
IF
