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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Casp1 - caspase 1
Alias:
ICE
Il1bc
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
具有半胱氨酸型内肽酶活性。参与几个过程,包括I-kappaB激酶/NF-kappaB信号传导的正调节;白细胞介素-1β生产的正调节;以及蛋白质自身加工。在几个过程的上游或内部发挥作用,包括膜超极化;线粒体去极化;以及白细胞介素-1α生产的正调节。位于细胞外区域。IPAF炎症小体复合物的一部分。在膝关节和肾单位表达。与人类CASP1(天冬氨酸蛋白酶1)正同源。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:12362
ENSEMBL:ENSMUSG00000025888
UNIPROT:P29452
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
12362
1
10
8765 bp
45.64
19
15
Casp1 Genetics information (+)
GRCm39
Sequence Homology
Transcripts & Proteins
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Transcript
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* This data comes from NCBI.
Gene Expression
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Name
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