人类

CCR6 - C-C Motif Chemokine Receptor 6

Alias:
BN-1
DCR2
DRY6
CCR-6
CD196
CKRL3
GPR29
CKR-L3
CMKBR6
GPRCY4
STRL22
CC-CKR-6
C-C CKR-6
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码β趋化因子受体家族的一员,预测是一个类似于G蛋白偶联受体的七跨膜蛋白。该基因在未成熟树突状细胞和记忆T细胞中优先表达。这个受体的配体是巨噬细胞炎性蛋白3α(MIP-3α)。这个受体已被证明对B系成熟和抗原驱动的B细胞分化非常重要,它可能调节在炎性和免疫应答过程中树突状细胞和T细胞的迁移和招募。这个基因的替代剪接转录变异体已经描述,它们编码相同的蛋白质。[由RefSeq,2008年7月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
3
3
27347 bp
42.49
12
2
9
11

CCR6 Genetics information (+)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Mutation Direct
Sequence
Comparison
Al agent
Tutorials
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