Enables protein serine/threonine kinase activity. Involved in regulation of neuron projection development and regulation of relaxation of cardiac muscle. Acts upstream of or within G1/S transition of mitotic cell cycle; calcium ion transport; and protein autophosphorylation. Located in postsynaptic density. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; integumental system; and sensory organ. Human ortholog(s) of this gene implicated in autosomal dominant non-syndromic intellectual disability. Orthologous to human CAMK2G (calcium/calmodulin dependent protein kinase II gamma). [provided by Alliance of Genome Resources, Apr 2022]