Log In|Sign Up
中文人类
CCR3 - C-C Motif Chemokine Receptor 3
Alias:
CKR3
CD193
CKR 3
CMKBR3
C C CKR3
CC-CKR-3
Favorite
这个基因编码的蛋白质是一种C-C型趋化因子受体，属于G蛋白偶联受体家族1。这个受体结合并响应多种趋化因子，包括eotaxin (CCL11)，eotaxin-3 (CCL26)，MCP-3 (CCL7)，MCP-4 (CCL13)和RANTES (CCL5)。它在嗜酸性粒细胞和嗜碱粒细胞中高度表达，也在TH1和TH2细胞以及气道上皮细胞中检测到。这个受体可能有助于嗜酸性粒细胞和其他炎性细胞在过敏气道中的积累和激活。它还已知是HIV-1的进入共受体。这个基因和另外七个趋化因子受体基因在染色体区域3p21上的趋化因子受体基因簇中形成。已经描述了可变剪接的转录变异体。[由RefSeq，2009年9月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
CCR3 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
