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中文小鼠
C2 - complement component 2 (within H-2S)
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这个基因编码补体系统经典途径的C2成分。编码的蛋白质经过C1成分的蛋白酶作用加工，形成C2a和C2b片段。C2a片段又选择性地切割补体系统的C3和C5成分。缺乏编码的蛋白质的小鼠对细菌感染更敏感。这个基因的人类同源基因的突变与疾病如系统性红斑狼疮、Henoch-Schonlein紫癜或多发性肌炎有关。[RefSeq,2015年3月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
C2 Genetics information (-)
GRCm39
Sequence Homology
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
References Literature
Title
PMID
Journal
Year
IF
