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中文小鼠
Btk - Bruton agammaglobulinemia tyrosine kinase
Alias:
xid
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激活蛋白质酪氨酸激酶活性。参与细胞因子产生的负调控。在几个过程的上游或内部发挥作用，包括B细胞亲和力成熟；I-kappaB激酶/NF-kappaB信号传导；以及B细胞增殖的负调控。位于细胞质囊泡和核中。在肝脏左叶；肝脏右叶；脾脏；和胸腺原基中表达。用于研究X-连锁无丙种球蛋白血症。该基因的人类同源物涉及无丙种球蛋白血症（多种）；孤立的生长激素缺乏症III型；和淋巴瘤（多种）。与人类BTK（Bruton酪氨酸激酶）正交。[由基因组资源联盟，2022年4月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
Btk Genetics information (-)
GRCm39
Sequence Homology
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
References Literature
Title
PMID
Journal
Year
IF
