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Btc - betacellulin, epidermal growth factor family member

Alias:
Bcn
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
这个基因编码表皮生长因子(EGF)家族的一员。这些生长因子是EGFR/ErbB受体酪氨酸激酶的配体,在细胞生长和分化中发挥作用。编码的蛋白质作为跨膜前体合成,通过蛋白水解切割生成成熟肽,在胰腺β细胞的分化中发挥作用。这个基因可能在急性胰腺炎中起到保护作用,而其表达增加可能参与糖尿病黄斑水肿。使用这个基因和其他胰腺特异性的转录因子的组合进行基因治疗可能诱导胰岛新生并改善1型糖尿病患者的血糖过高。[RefSeq,2011年4月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
1
6
45734 bp
19.66
5
11

Btc Genetics information (-)

GRCm39

Sequence Homology

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Sequence
Comparison
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