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中文小鼠
Bmpr2 - bone morphogenetic protein receptor, type II (serine/threonine kinase)
Alias:
BMP-2
BRK-3
BMPR-2
BMPRII
BMPR-II
Gm20272
2610024H22Rik
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这个基因编码一种丝氨酸/苏氨酸激酶，作为骨形态发生蛋白（BMPs）的受体发挥作用。编码的蛋白质是一种II型受体，结合细胞外的BMPs并在细胞膜上形成两个II型和两个I型受体的复合物。这个复合物信号向下传递，激活SMAD转录调节因子。这种信号传导在胚胎发育过程中非常重要。这个基因的突变可能导致肺动脉高压。[RefSeq,2013年3月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
Bmpr2 Genetics information (+)
GRCm39
Sequence Homology
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
References Literature
Title
PMID
Journal
Year
IF
