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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Bmp6 - bone morphogenetic protein 6
Alias:
Vgr1
D13Wsu115e
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
这个基因编码一种分泌性的TGF-beta(转化生长因子-β)蛋白质超家族的配体。这个家族的配体结合各种TGF-beta受体,导致SMAD家族转录因子的招募和激活,从而调控基因表达。编码的前原蛋白在蛋白水解过程中被加工,生成二硫键连接的同源二聚体的各个亚基。这个蛋白质调控广泛的生物过程,包括铁稳态、脂肪和骨发育以及排卵。缺乏这个基因的小鼠表现出胸骨骨化延迟、铁过载以及雌性生育力降低。[由RefSeq,2016年7月提供]
Related ID:
NCBI:12161
ENSEMBL:ENSMUSG00000039004
UNIPROT:P20722
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
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Reference
12161
1
7
155186 bp
56.43
7
16
Bmp6 Genetics information (+)
GRCm39
Sequence Homology
Transcripts & Proteins
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Transcript
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* This data comes from NCBI.
Gene Expression
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