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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Bmi1 - Bmi1 polycomb ring finger oncogene
Alias:
Bmi-1
Pcgf4
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
这个句子很长,我将为您提取关键信息并翻译成中文。 这个基因编码一个蛋白质,具有以下功能: 1. 激活RNA聚合酶II的顺式调控区域,实现序列特异性的DNA结合活性 2. 启动子特异性的染色质结合活性 3. 泛素-蛋白转移酶激活活性 这个基因参与以下生物学过程: 1. 正调控B细胞的增殖 2. 正调控未成熟胸腺T细胞的增殖 3. 在多个过程的上游或内部发挥作用,包括脊索动物胚胎发育、组蛋白修饰和腺上/腺下模式形成的调控 这个基因位于异染色质和核体中,是PcG蛋白复合物和泛素连接酶复合物的一部分。它在多个结构中表达,包括消化系统、泌尿系统、神经系统、呼吸系统和感受器器官。这个基因的人类同源物与急性髓细胞白血病、结直肠癌和肝细胞癌有关。它与几个人类基因,包括COMMD3-BMI1(COMMD3-BMI1贯通)有同源性。
Related ID:
NCBI:12151
ENSEMBL:ENSMUSG00000026739
UNIPROT:P25916
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
12151
5
10
9488 bp
36.71
13
7
Bmi1 Genetics information (+)
GRCm39
Sequence Homology
Transcripts & Proteins
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#
Transcript
Length(nt)
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CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
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Cell-specific RNA expression
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Interactions
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Type
Name
MGI
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References Literature
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