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中文人类
LRRK2 - Leucine Rich Repeat Kinase 2
Alias:
PARK8
RIPK7
ROCO2
AURA17
DARDARIN
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这个基因是富含亮氨酸重复序列激酶家族的成员，编码一个具有ankryin重复区域、亮氨酸丰富重复（LRR）结构域、激酶结构域、DFG样基序、RAS结构域、GTP酶结构域、MLK样结构域和WD40结构域的蛋白质。该蛋白质主要存在于细胞质中，但也与线粒体外膜结合。这个基因的突变与帕金森病-8有关。[由RefSeq，2008年7月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
LRRK2 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
