小鼠

Bcl2l1 - BCL2-like 1

Alias:
BclX
Bcl2l
bcl-x
Bcl-XL
Bcl(X)L
bcl2-L-1
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
这个基因编码Bcl-2家族中一个凋亡调节因子成员。编码的蛋白质定位在内质网和线粒体外膜,并调控发育和组织内环境稳定过程中的程序性细胞死亡途径。这个蛋白质与线粒体外膜上的电压依赖性阴离子通道结合,促进钙离子的摄入。缺乏这个基因的小鼠胚胎可以存活两周,并表现出不成熟造血细胞和神经元的细胞死亡。可变剪接产生多个转录子变异体。这个基因的其他可变剪接转录变异体已经被描述,但它们的全长性质尚不清楚。[由RefSeq,2014年1月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
9
3
72981 bp
26.13
11
16

Bcl2l1 Genetics information (-)

GRCm39

Sequence Homology

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Sequence
Comparison
Al agent
Tutorials
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