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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Bcl2l1 - BCL2-like 1
Alias:
BclX
Bcl2l
bcl-x
Bcl-XL
Bcl(X)L
bcl2-L-1
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
这个基因编码Bcl-2家族中一个凋亡调节因子成员。编码的蛋白质定位在内质网和线粒体外膜,并调控发育和组织内环境稳定过程中的程序性细胞死亡途径。这个蛋白质与线粒体外膜上的电压依赖性阴离子通道结合,促进钙离子的摄入。缺乏这个基因的小鼠胚胎可以存活两周,并表现出不成熟造血细胞和神经元的细胞死亡。可变剪接产生多个转录子变异体。这个基因的其他可变剪接转录变异体已经被描述,但它们的全长性质尚不清楚。[由RefSeq,2014年1月提供]
Related ID:
NCBI:12048
ENSEMBL:ENSMUSG00000007659
UNIPROT:Q64373
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
12048
9
3
72981 bp
26.13
11
16
Bcl2l1 Genetics information (-)
GRCm39
Sequence Homology
Transcripts & Proteins
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#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
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Interactions
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Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
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Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available
References Literature
Title
PMID
Journal
Year
IF
No Data Found!
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