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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Bax - BCL2-associated X protein
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
激活Hsp70蛋白结合活性;分子伴侣结合活性;以及相同蛋白质结合活性。参与胱氨酸型内肽酶活性的激活,该活性涉及凋亡过程。在几个过程的上游或内部发挥作用,包括动物器官发育;凋亡信号通路;以及凋亡过程的调节。位于细胞质;内质网;和线粒体外膜。是BAX复合物的一部分。在几个结构中表达,包括消化系统;鳃弓;中枢神经系统;生殖泌尿系统;和感觉器官。该基因的人类同源物涉及急性成淋巴细胞白血病;Ataxia Telangiectasia;结肠癌;结直肠癌;和肺癌。与人类BAX(BCL2相关X,凋亡调节剂)正交。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:12028
ENSEMBL:ENSMUSG00000003873
UNIPROT:Q07813
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
12028
5
6
5209 bp
21.39
8
13
Bax Genetics information (-)
GRCm39
Sequence Homology
Transcripts & Proteins
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* This data comes from NCBI.
Gene Expression
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Name
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