Bad - BCL2-associated agonist of cell death

Enables cysteine-type endopeptidase activator activity involved in apoptotic process and protein phosphatase binding activity. Involved in several processes, including positive regulation of cell communication; positive regulation of glucokinase activity; and positive regulation of mitochondrial membrane potential. Acts upstream of or within several processes, including apoptotic signaling pathway; modulation by virus of host apoptotic process; and positive regulation of lymphocyte differentiation. Located in cytosol and mitochondrion. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system gland; and liver and biliary system. Human ortholog(s) of this gene implicated in endometrial cancer; lung non-small cell carcinoma; and pancreatic cancer. Orthologous to human BAD (BCL2 associated agonist of cell death). [provided by Alliance of Genome Resources, Apr 2022]