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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Axin1 - axin 1
Alias:
Fu
Kb
Ki
Axin
fused
kinky
knobbly
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
具有多种功能,包括SMAD结合活性;β-连环蛋白结合活性;和酶结合活性。参与正向调节JNK级联;正向调节蛋白质修饰过程;和正向调节DNA模板的转录。在几个过程的上游或内部发挥作用,包括脊索动物胚胎发育;大分子代谢过程的负向调节;和蛋白质代谢过程的调节。位于几个细胞组件中,包括细胞皮质;胞质囊泡;和微管细胞骨架。是Wnt信号复合体和β-连环蛋白降解复合体的一部分。在几个结构中表达,包括消化系统;前脑;生殖泌尿系统;血细胞淋巴系统腺体;和视网膜。该基因的人类同源物与肝细胞癌有关。与人类AXIN1(轴蛋白1)正交。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:12005
ENSEMBL:ENSMUSG00000024182
UNIPROT:O35625
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
12005
6
11
64491 bp
96.28
13
16
Axin1 Genetics information (+)
GRCm39
Sequence Homology
Transcripts & Proteins
Table View
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#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
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Interactions
Reset
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available
References Literature
Title
PMID
Journal
Year
IF
No Data Found!
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