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Aup1 - ancient ubiquitous protein 1

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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
这个基因编码的蛋白质包含几个保守结构域,包括一个疏水结构域,一个乙酰转移酶结构域,一个泛素结合结构域,以及一个招募泛素结合酶E2 G2 (Ube2g2)所需的结构域。在人类中,这种蛋白质定位在内质网和脂质滴上。该蛋白质被认为既参与内质网中错误折叠蛋白质的降解,又参与中性脂质的储存。这个基因的人类同源物的表达减少会强烈减少细胞中脂质滴的聚集,并导致错误折叠蛋白质的稳定化。可变剪接导致多个转录变异体。[由RefSeq,2014年8月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
2
12
3181 bp
46.12
--
10

Aup1 Genetics information (+)

GRCm39

Sequence Homology

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Sequence
Comparison
Al agent
Tutorials
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