人类

CLK2 - CDC Like Kinase 2

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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码一个双特异性蛋白激酶,可以磷酸化含有丝氨酸/苏氨酸和酪氨酸的底物。这个蛋白质的活性可以调节剪接体复合物的富含丝氨酸和精氨酸(SR)的蛋白质,从而影响选择性转录剪接。染色体上的这个基因座与染色体19上的PAFAH1B3(血小板激活因子乙酰水解酶1b,催化亚基3(29kDa))基因之间已经描述了染色体易位,从而产生了融合蛋白。注意这个基因与TELO2基因(GeneID:9894)不同,后者共享CLK2别名,但编码的蛋白质参与端粒长度调节。这个基因在染色体7上有一个假基因。选择性剪接产生了多种转录变异体。[由RefSeq,2014年6月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
9
13
10637 bp
60.09
29
--
5
18

CLK2 Genetics information (-)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Comparison
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