Atf2 - activating transcription factor 2

Enables several functions, including DNA-binding transcription activator activity, RNA polymerase II-specific; cAMP response element binding activity; and protein dimerization activity. Involved in several processes, including animal organ development; histone acetylation; and intracellular signal transduction. Acts upstream of or within with a positive effect on regulation of transcription by RNA polymerase II. Acts upstream of or within several processes, including adipose tissue development; fat cell differentiation; and positive regulation of transforming growth factor beta2 production. Located in membrane; nucleus; and site of double-strand break. Is expressed in several structures, including alimentary system; brain; eye; genitourinary system; and musculoskeletal system. Used to study meconium aspiration syndrome and osteochondrodysplasia. Orthologous to human ATF2 (activating transcription factor 2). [provided by Alliance of Genome Resources, Apr 2022]