小鼠

Artn - artemin

Alias:
neublastin
Favorite
Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
这个基因编码一种胶质细胞系衍生神经营养因子(GDNF)亚家族和TGF-β(转化生长因子-β)蛋白质超家族的分泌配体。这个家族的配体与各种TGF-β受体结合,导致SMAD家族转录因子的招募和激活,从而调控基因表达。编码的前原原蛋白在蛋白水解过程中被加工,生成二硫键连接的同源二聚体的各个亚基。这个蛋白通过RET受体和GFR alpha 3核心受体传递信号,并支持许多外周神经元群体和至少一个多巴胺能CNS神经元的生存。缺乏这个基因功能拷贝的小鼠表现出下垂和交感神经系统发育受损。[RefSeq,2016年8月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
11
5
4889 bp
23.73
2
4

Artn Genetics information (-)

GRCm39

Sequence Homology

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
Wechat
Sequence
Comparison
Al agent
Tutorials
Back to top