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Bmal1 - basic helix-loop-helix ARNT like 1

Alias:
MOP3
Arnt3
Arntl
BMAL1b
bHLHe5
bmal1b'
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
这个基因编码的蛋白质是一种与Clock形成异二聚体的基本螺旋-环-螺旋蛋白。这个异二聚体结合周期基因(Per1、Per2、Per3)和隐花色素基因(Cry1、Cry2)上游的E-box增强子元件,并激活这些基因的转录。Per和Cry蛋白通过与其自身的反馈循环中的Clock/Arntl复合物相互作用而异二聚化并抑制它们的自身转录。这个基因的缺陷与不育、糖异生和脂肪生成问题以及睡眠模式的改变有关。已经发现这个基因有两个编码不同异型体的转录变异体。[由RefSeq,2014年1月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
23
21
135514 bp
69.45
21
94

Bmal1 Genetics information (+)

GRCm39

Sequence Homology

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Sequence
Comparison
Al agent
Tutorials
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