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中文人类
EXOSC6 - Exosome Component 6
Alias:
p11
EAP4
MTR3
Mtr3p
hMtr3p
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这个基因产物构成了被称为外泌体（exosome）的多亚基颗粒的亚单位之一，外泌体参与mRNA的降解。人类外泌体的组成与其酵母对应物相似。这种蛋白质与酵母Mtr3蛋白质同源。其确切功能尚不清楚，但已使用无细胞RNA衰减系统表明，外泌体是降解含有丰富AU元素（AREs）的不稳定mRNA所必需的，但不是聚(A)缩短所必需的。外泌体本身不识别含有ARE的mRNA，但需要可以与外泌体相互作用并将其招募到不稳定mRNA的ARE结合蛋白，从而促进它们的快速降解。[由RefSeq，2008年7月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
EXOSC6 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
