小鼠

Apoe - apolipoprotein E

Alias:
Apo-E
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
这个基因编码载脂蛋白A1/A4/E家族蛋白质的一员。这种蛋白质参与血液中脂蛋白的运输。它结合特定的肝脏和外周细胞受体,对富含甘油三酯的脂蛋白成分的正常分解代谢至关重要。这个基因的纯合子敲除小鼠在血液中胆固醇水平积累过高,并发展为动脉粥样硬化。这个基因的不同等位基因与阿尔茨海默病患者患病风险增加或保护作用有关。这个基因在染色体7上与相关载脂蛋白C1、C2和C4基因聚类。[由RefSeq提供,2015年4月]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
5
4
4158 bp
35.87
42
19

Apoe Genetics information (-)

GRCm39

Sequence Homology

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Sequence
Comparison
Al agent
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