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Birc2 - baculoviral IAP repeat-containing 2

Alias:
Api1
Api2
IAP1
IAP2
MIHB
MIHC
Birc3
HIAP1
HIAP2
MIAP1
MIAP2
RNF48
cIAP1
cIAP2
C-IAP1
mcIAP1
C330006D17Rik
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
该基因预测具有多种功能,包括与FBXO家族蛋白结合活性、分子伴侣结合活性和涉及凋亡过程的半胱氨酸内肽酶抑制剂活性。它还参与坏死性凋亡过程。该基因在上游或几个过程中发挥作用,包括细胞对肿瘤坏死因子的反应、坏死性凋亡过程的负调控以及涉及坏死性凋亡过程的ripoptosome组装的负调控。该基因位于质膜的细胞质侧,是CD40受体复合物的一部分。它在脑室层、生殖泌尿系统和胸腺原基中表达。该基因的人类同源物与乳腺癌有关。该基因与人类BIRC2(包含杆状病毒IAP重复序列2)正交。[由基因组资源联盟,2022年4月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
7
8
18897 bp
69.68
10
6

Birc2 Genetics information (-)

GRCm39

Sequence Homology

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Sequence
Comparison
Al agent
Tutorials
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