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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Atg5 - autophagy related 5
Alias:
Apg5l
Atg5l
Paddy
2010107M05Rik
3110067M24Rik
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
这个基因编码的蛋白质与自噬蛋白12结合,作为泛素样结合系统中的E1样激活酶。该编码的蛋白质参与多种细胞过程,包括自噬囊泡形成、氧化损伤后的线粒体质量控制、先天抗病毒免疫应答的负调控、淋巴细胞发育和增殖、MHC II抗原呈递、脂肪细胞分化和凋亡。已发现这个基因有两个转录变异体,编码不同的蛋白质异构体。[RefSeq, 2015年9月提供]
Related ID:
NCBI:11793
ENSEMBL:ENSMUSG00000038160
UNIPROT:Q99J83
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
11793
5
8
95971 bp
32.40
8
19
Atg5 Genetics information (+)
GRCm39
Sequence Homology
Transcripts & Proteins
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#
Transcript
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CDS(bp)
Protein
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* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
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Name
MGI
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References Literature
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