小鼠

Prdx6 - peroxiredoxin 6

Alias:
GPx
Aop2
CP-3
Ltw4
Ltw-4
NSGPx
ORF06
Prdx5
Brp-12
Lvtw-4
aiPLA2
LPCAT-5
1-cysPrx
1-Cys Prx
9430088D19Rik
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
这个基因编码过氧化物还原酶家族的过氧化物酶成员。编码的蛋白质是一种具有谷胱甘肽过氧化物酶和磷脂酶活性的双功能酶。这种蛋白质是一种抗氧化剂,可以减少过氧化膜磷脂,并在磷脂稳态中扮演重要角色,基于其产生溶血磷脂底物以用于磷脂合成的重建途径。缺乏这个基因的小鼠对氧化应激敏感,肺磷脂代谢改变,并容易患皮肤肿瘤。这个基因的可变剪接导致多个转录变异体。这个基因的一个假基因位于染色体4上。[由RefSeq,2014年12月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
3
5
11099 bp
24.87
11
17

Prdx6 Genetics information (-)

GRCm39

Sequence Homology

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Sequence
Comparison
Al agent
Tutorials
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