Ptpn2 - protein tyrosine phosphatase, non-receptor type 2

Enables non-membrane spanning protein tyrosine phosphatase activity. Predicted to be involved in several processes, including hemopoiesis; negative regulation of leukocyte differentiation; and regulation of signal transduction. Predicted to act upstream of or within negative regulation of transcription by RNA polymerase II and protein dephosphorylation. Predicted to be located in several cellular components, including endoplasmic reticulum; endoplasmic reticulum-Golgi intermediate compartment; and nucleoplasm. Predicted to colocalize with plasma membrane. Orthologous to human PTPN2 (protein tyrosine phosphatase non-receptor type 2). [provided by Alliance of Genome Resources, Apr 2022]