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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Alox5 - arachidonate 5-lipoxygenase
Alias:
5LO
5LX
5-LO
5-LOX
F730011J02
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
激活花生四烯酸5-脂氧酶活性。参与几个过程,包括白细胞迁移;负调控血管生成;以及调控细胞对压力的反应。在白细胞三烯生物合成过程和与炎症反应相关的白细胞三烯产生中起上游或内部作用。位于细胞质和细胞核中。在十二指肠上皮和小肠上皮中表达。此基因的人类同源物与动脉疾病(多种);哮喘(多种);胰腺癌;和肺结核有关。与人类ALOX5(花生四烯酸5-脂氧酶)正交。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:11689
ENSEMBL:ENSMUSG00000025701
UNIPROT:P48999
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
11689
2
14
51110 bp
77.97
6
17
Alox5 Genetics information (-)
GRCm39
Sequence Homology
Transcripts & Proteins
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* This data comes from NCBI.
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Name
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