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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
大鼠
Mapk1 - mitogen activated protein kinase 1
Alias:
ERT1
Erk2
ERK-2
p42-MAPK
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
激活多种功能,包括ATP结合活性;MAP激酶活性;和促有丝分裂激活的蛋白激酶激酶结合活性。参与多种过程,包括ERK1和ERK2级联反应;蜕膜化;和宏分子生物合成过程的正向调节。在肽酰-丝氨酸磷酸化上游发挥作用。位于多种细胞组件中,包括小凹;树突质;和胞质。是蛋白质含有复合物的一部分。在突触后密度中活跃。用于研究冠状动脉硬化(多种);胃溃疡;大脑中动脉梗死;2型糖尿病;和输尿管梗阻。肾纤维化和中尿管梗阻的生物标志物。该基因的人类同源物涉及诺尼汉综合征13;腺癌(多种);肺动脉高压;和肾细胞癌。与人MAPK1(促有丝分裂激活的蛋白激酶1)正交。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:116590
ENSEMBL:ENSRNOG00000001849
UNIPROT:P63086
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
116590
3
9
65817 bp
41.28
16
24
Mapk1 Genetics information (-)
mRatBN7.2
Sequence Homology
Transcripts & Proteins
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#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
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* This data comes from NCBI.
Gene Expression
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Name
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