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中文人类
SLC22A12 - Solute Carrier Family 22 Member 12
Alias:
RST
UAT
OAT4L
URAT1
hURAT1
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这个基因编码的蛋白质是有机阴离子转运体（OAT）家族的一员，作为尿酸盐转运体调节血液中的尿酸盐水平。这种蛋白质主要是一个整合膜蛋白，主要存在于肾脏近端小管的上皮细胞中。血清尿酸盐水平升高（高尿酸血症）与痛风发病率增加有关，而此基因的突变导致肾型1型低尿酸血症。可变剪接导致多个转录变异体。[RefSeq，2013年1月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
SLC22A12 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
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Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
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Tile View
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Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
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Reference
Score
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Name
MGI
Strain of Origin
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Mutations
Related Drugs
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CAS Number
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References Literature
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