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Ager - advanced glycosylation end product-specific receptor

Alias:
RAGE
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
具有S100蛋白结合活性;高级糖基化终末产物结合活性;和肝素结合活性。参与几个过程,包括对淀粉样β的细胞反应;长期突触增强的负调控;和细胞因子产生的正调控。在几个过程的上游或内部发挥作用,包括正趋化性的诱导;高级糖基化终末产物受体活性的负调控;和大分子代谢过程的正调控。位于细胞外空间和质膜上。在几个结构中表达,包括消化系统;大脑;生殖泌尿系统;血淋巴样系统腺体;和肺。这个基因的人类同源物涉及几种疾病,包括自身免疫疾病(多种);心血管系统疾病(多种);囊性纤维化;肾衰竭(多种);和狼疮性肾炎。正交人类AGER(高级糖基化终末产物特异性受体)。[由基因组资源联盟,2022年4月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
5
11
3367 bp
42.65
13
15

Ager Genetics information (+)

GRCm39

Sequence Homology

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Sequence
Comparison
Al agent
Tutorials
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