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中文人类
TNFRSF13C - TNF Receptor Superfamily Member 13C
Alias:
BAFFR
CD268
CVID4
BAFF-R
BROMIX
prolixin
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B细胞激活因子(BAFF)在体外增强B细胞存活，并作为外周B细胞群落的调节者。在小鼠中过表达BAFF会导致成熟B细胞增生过度和系统性红斑狼疮(SLE)的症状。此外，一些SLE患者的血清中BAFF水平升高。因此，有研究表明，异常高水平的BAFF可能通过增强自身反应B细胞的存活来参与自身免疫性疾病的病理发生。这个基因编码的蛋白质是BAFF的受体，是一种含有单个细胞外富含半胱氨酸结构的III型跨膜蛋白。据认为，这个受体是BAFF介导的成熟B细胞存活所需的主要受体。[由RefSeq，2008年7月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
TNFRSF13C Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
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Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
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Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
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Interactions
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Regulation
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Score
Related Mouse Models
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Name
MGI
Strain of Origin
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Mutations
Related Drugs
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References Literature
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