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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Cfd - complement factor D (adipsin)
Alias:
DF
Adn
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
这个基因编码一种丝氨酸蛋白酶,在补体激活的替代途径中扮演重要角色,用于识别和消除病原体。编码的前原原蛋白经历蛋白水解加工,生成具有活性的成熟酶,进而切割补体途径中的因子B。这个基因在脂肪细胞中表达,成熟的酶分泌到血流中。缺乏编码产物的鼠无法启动补体激活的替代途径。[RefSeq,2016年7月提供]
Related ID:
NCBI:11537
ENSEMBL:ENSMUSG00000061780
UNIPROT:P03953
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
11537
3
5
1803 bp
28.06
7
13
Cfd Genetics information (+)
GRCm39
Sequence Homology
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* This data comes from NCBI.
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