小鼠

Adam17 - a disintegrin and metallopeptidase domain 17

Alias:
Tace
CD156b
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
这个基因编码一个整合素和金属蛋白酶(ADAM)家族的成员,该家族在包括细胞信号传导、粘附和迁移等各种生物过程中发挥重要作用的内切蛋白酶。编码的前原蛋白经历蛋白水解加工,生成参与称为外域切割的膜结合蛋白蛋白水解释放过程的成熟酶。缺乏编码的蛋白质的小鼠在子宫内死亡或在出生后一周内无法存活。可选的剪接导致多个转录变异体,它们编码不同的异构体,其中一些可能经历类似的加工过程。[RefSeq,2016年5月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
4
19
50124 bp
93.06
20
13

Adam17 Genetics information (-)

GRCm39

Sequence Homology

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Sequence
Comparison
Al agent
Tutorials
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