人类

TMEM123 - Transmembrane Protein 123

Alias:
KCT3
PORMIN
PORIMIN
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码一个高度糖基化的跨膜蛋白,其细胞外结构域中含有大量苏氨酸和丝氨酸残基,类似于广义上称为黏附素的蛋白质类别。某些细胞类型暴露于抗PORIMIN(诱导膜损伤的肿瘤相关受体)抗体时,该蛋白在细胞表面上交联并诱导一种称为oncosis的细胞死亡类型。Oncosis不同于凋亡,其特点是细胞膜完整性丧失,而无DNA碎片。这个基因产物被提议作为细胞表面受体,调节细胞死亡。[RefSeq,2008年7月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
1
5
56434 bp
21.53
6
--
4
6

TMEM123 Genetics information (-)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Sequence
Comparison
Al agent
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