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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Adam10 - a disintegrin and metallopeptidase domain 10
Alias:
kuz
MADM
kuzbanian
1700031C13Rik
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
这个基因编码一个整合素和金属蛋白酶(ADAM)家族的成员,该家族在包括细胞信号传导、粘附和迁移等各种生物过程中发挥重要作用的内切蛋白酶。编码的前原原蛋白经历蛋白水解加工,生成成熟的酶,该酶涉及称为外域切割的膜结合蛋白的蛋白水解释放过程。缺乏编码的蛋白质的小鼠在胚胎期内死亡,发育中的中枢神经系统、体节和心血管系统存在多种缺陷。[RefSeq,2016年5月提供]
Related ID:
NCBI:11487
ENSEMBL:ENSMUSG00000054693
UNIPROT:O35598
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
11487
2
16
101379 bp
83.97
11
18
Adam10 Genetics information (+)
GRCm39
Sequence Homology
Transcripts & Proteins
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Transcript
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* This data comes from NCBI.
Gene Expression
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Name
MGI
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