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Dusp1 - dual specificity phosphatase 1

Alias:
Mkp1
CL100
MKP-1
3CH134
Ptpn16
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
促进生长因子结合活性与蛋白质酪氨酸/苏氨酸磷酸酶活性。参与几个过程,包括ERK1和ERK2级联的负调控;调控凋亡过程;以及响应睾酮。位于细胞核中。用于研究亨廷顿病。自身免疫疾病(多种)的生物标志;脑疾病(多种);高血压;胰腺炎;和门静脉高压。这个基因的人类同源物与乳腺癌有关。与人类DUSP1(双特异性磷酸酶1)正交。[由基因组资源联盟,2022年4月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
1
14
2798 bp
39.54
7
5

Dusp1 Genetics information (+)

mRatBN7.2

Sequence Homology

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Sequence
Comparison
Al agent
Tutorials
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