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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
大鼠
Cdkn1a - cyclin-dependent kinase inhibitor 1A
Alias:
Cip1
UV96
Waf1
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Description
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
该基因预测具有多种功能,包括细胞周期蛋白结合活性、酶结合活性和蛋白激酶调节活性。参与多个过程,包括肠道上皮细胞成熟、对皮质酮的反应和对高氧气的反应。位于细胞核和核周质中。是常染色体显性多囊肾病的生物标志物,以及高血压(多种)、脂性肾病、肝脏良性肿瘤和癌前肿瘤。该基因的人类同源物与几种疾病有关,包括非小细胞肺癌、青光眼、口腔粘膜白斑、口腔鳞状细胞癌和原发性开角型青光眼。与人类CDKN1A(细胞周期依赖性激酶抑制剂1A)正交。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:114851
ENSEMBL:ENSRNOG00000000521
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
114851
4
3
10551 bp
Unknown
17
5
Cdkn1a Genetics information (+)
mRatBN7.2
Sequence Homology
Transcripts & Proteins
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Transcript
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* This data comes from NCBI.
Gene Expression
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