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中文人类
TIRAP - TIR Domain Containing Adaptor Protein
Alias:
Mal
wyatt
BACTS1
MyD88-2
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先天免疫系统通过识别微生物病原体的Toll样受体(TLRs)来识别病原相关分子模式。不同的TLR识别不同的病原相关分子模式，所有TLR都具有负责信号转导的Toll白介素1受体(TIR)结构域。该基因编码的蛋白质是一种参与免疫系统TLR4信号通路的中介蛋白质。它激活NF-kappa-B、MAPK1、MAPK3和JNK，然后导致细胞因子分泌和炎症反应。该基因的可变剪接导致几种转录变异体；然而，并非所有变异体都已完全描述。[RefSeq，2008年7月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
TIRAP Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
