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中文大鼠
Braf - B-Raf proto-oncogene, serine/threonine kinase
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激活MAP激酶激酶激酶活性；有丝分裂激活的蛋白质激酶激酶结合活性；和小GTP酶结合活性。参与几个过程，包括细胞对神经生长因子刺激的响应；正向调节ERK1和ERK2级联；和响应cAMP。位于神经元突起；核；和质膜上。用于研究胆管腺瘤；胆管癌；肝内胆管癌；和甲状腺乳头状癌。这个基因的人类同源物与几种疾病有关，包括Noonan综合征7；癌（多种）；卡西奥脸皮综合症（多种）；中枢神经系统良性肿瘤（多种）；和黑素瘤（多种）。与人类BRAF（B-Raf原癌基因，丝氨酸/苏氨酸激酶）正交。[由基因组资源联盟，2022年4月提供]
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Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
Braf Genetics information (-)
mRatBN7.2
Sequence Homology
Transcripts & Proteins
Table View
Tile View
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Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
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Abundance
Alphabetical
Cell-specific RNA expression
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Abundance
Alphabetical
Interactions
Acting
Regulation
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MGI
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References Literature
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