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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Chrnb2 - cholinergic receptor, nicotinic, beta polypeptide 2 (neuronal)
Alias:
Acrb2
Acrb-2
[b]2-nAchR
C030030P04Rik
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
乙酰胆碱门控阳离子选择通道活性。参与突触囊泡外泌体的调节。在多个过程的上游或内部发挥作用,包括学习或记忆;神经系统发育;以及昼夜睡眠/觉醒周期的调节,睡眠。位于质膜的外侧。是突触后特化膜的整合成分和突触前膜的整合成分。是乙酰胆碱门控通道复合物的组成部分。在胆碱能突触和多巴胺能突触中活跃。在包括消化系统;泌尿生殖系统;皮肤系统;神经系统;和感觉器官在内的几个结构中表达。用于研究注意力缺陷多动障碍;自闭症谱系障碍;和常染色体显性夜间前额叶癫痫3。这个基因的人类同源物与常染色体显性夜间前额叶癫痫和常染色体显性夜间前额叶癫痫3有关。与人类CHRNB2(胆碱能受体烟碱β2亚单位)正交。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:11444
ENSEMBL:ENSMUSG00000027950
UNIPROT:Q9ERK7
Basic Information
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11444
3
6
11185 bp
57.11
10
4
Chrnb2 Genetics information (-)
GRCm39
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* This data comes from NCBI.
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