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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Macf1 - microtubule-actin crosslinking factor 1
Alias:
Acf7
MACF
Aclp7
ABP620
mKIAA0465
mKIAA0754
D830031N03Rik
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
激活肌动蛋白结合活性和微管结合活性。参与几个过程,包括Wnt信号通路的正调控;聚焦粘附组装的调控;以及神经元突起分支的调控。在几个过程的上游或内部发挥作用,包括Wnt信号通路;中胚层的形成;以及蛋白质在质膜内的翻译后定位。位于细胞质;细胞骨架;以及突触后密度。在几个结构中表达,包括中枢神经系统;生殖泌尿系统;肢段;肺;以及骨骼肌。这个基因的人类同源物与具有复杂脑干畸形的小头畸形9有关。与人类的MACF1(微管肌动蛋白交联因子1)正交。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:11426
ENSEMBL:ENSMUSG00000028649
UNIPROT:Q69ZZ9
Basic Information
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Transcripts
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Length
MW (kDa)
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11426
20
99
338209 bp
Unknown
7
6
Macf1 Genetics information (-)
GRCm39
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* This data comes from NCBI.
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