大鼠

Dnm1l - dynamin 1-like

Alias:
DLP1
Drp1
Dnml1
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
使BH2结构域结合活性正常发挥作用;与clathrin结合;以及相同蛋白质结合活性。参与几个过程,包括线粒体组织结构、细胞组件组织的正向调节以及突触囊泡的回收。位于几个细胞组件中,包括高尔基膜、核周质区域和过氧化物酶体。在突触前内吞区膜和突触囊泡膜中活跃。与clathrin覆盖的小坑和线粒体膜共定位。慢性肾病、牙科氟中毒、肺纤维化、2型糖尿病的生物标志物。该基因的人类同源物与由于线粒体和过氧化物酶体分裂缺陷1导致的脑病以及视神经萎缩5有关。与人类DNM1L(动力蛋白1样)正交。[由基因组资源联盟,2022年4月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
15
19
51167 bp
83.91
13
12

Dnm1l Genetics information (+)

mRatBN7.2

Sequence Homology

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Sequence
Comparison
Al agent
Tutorials
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