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Nkx2-5 - NK2 homeobox 5

Alias:
Csx
Nkx2.5
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
具有多种功能,包括DNA结合转录因子活性;组蛋白去乙酰化酶结合活性;以及相同蛋白质结合活性。参与多种过程,包括细胞对过氧化氢的反应;RNA聚合酶II对转录的负调控;以及雌二醇的反应。位于细胞核中。肺纤维化的生物标志物。该基因的人类同源物涉及主动脉瓣病2;房室传导阻滞;先天性心脏病(多种);以及先天性无甲状腺功能减退症5。与人类NKX2-5(NK2 homeobox 5)正交。[由基因组资源联盟,2022年4月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
2
2
6577 bp
34.34
28
--

Nkx2-5 Genetics information (+)

mRatBN7.2

Sequence Homology

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Sequence
Comparison
Al agent
Tutorials
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