Sncb - synuclein, beta

Enables alpha-tubulin binding activity and beta-tubulin binding activity. Predicted to be involved in several processes, including chemical synaptic transmission; regulation of neuron death; and synaptic vesicle endocytosis. Predicted to act upstream of or within dopamine metabolic process and negative regulation of neuron apoptotic process. Located in growth cone; neuronal cell body; and terminal bouton. Is active in presynaptic cytosol. Used to study uveitis. Human ortholog(s) of this gene implicated in Lewy body dementia and Parkinson's disease. Orthologous to human SNCB (synuclein beta). [provided by Alliance of Genome Resources, Apr 2022]