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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Acadl - acyl-Coenzyme A dehydrogenase, long-chain
Alias:
LCAD
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
这个基因编码一个四聚体的线粒体黄素蛋白,是酰基CoA脱氢酶家族的成员。这个家族的成员催化脂肪酸β-氧化的第一步,在FAD依赖的反应中形成一个C2-C3反式双键。随着β-氧化经过其四个步骤,每个酰基CoA脱氢酶家族的成员在最佳的脂肪酸链长度下工作。这个酶在C12-和C16-酰基CoA之间具有最佳长度。在小鼠中,这个基因的缺陷可能导致突然死亡、心肌病以及耐受不了饥饿和寒冷。[RefSeq,2012年11月提供]
Related ID:
NCBI:11363
ENSEMBL:ENSMUSG00000026003
UNIPROT:P51174
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
11363
1
11
32471 bp
47.91
3
10
Acadl Genetics information (-)
GRCm39
Sequence Homology
Transcripts & Proteins
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Transcript
Length(nt)
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* This data comes from NCBI.
Gene Expression
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Name
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