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中文小鼠
Aanat - arylalkylamine N-acetyltransferase
Alias:
Nat4
Snat
Nat-2
AA-NAT
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这个基因编码的蛋白质属于乙酰转移酶超家族。它是褪黑素合成中的倒数第二酶，并控制脊椎动物松果腺中褪黑素产生的昼夜节律。褪黑素对于调节影响活动和睡眠的生理节律是必不可少的。这个酶受到cAMP依赖性磷酸化的调节，促进其与14-3-3蛋白的相互作用，从而保护酶免受蛋白酶体降解。这个基因可能参与多种遗传疾病，如延迟性睡眠相综合症。可变剪接导致多个转录子变异。[RefSeq,2010年1月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
Aanat Genetics information (+)
GRCm39
Sequence Homology
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
References Literature
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PMID
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