Log In|Sign Up
中文人类
PDCD10 - Programmed Cell Death 10
Alias:
CCM3
TFAR15
Favorite
这个基因编码一个与细胞凋亡相关的保守蛋白。该蛋白与丝氨酸/苏氨酸蛋白激酶MST4相互作用，以调节细胞外信号调节激酶(ERK)途径。它还可以与丝氨酸/苏氨酸激酶25相互作用并被其磷酸化，被认为在血管发育的基本信号传导途径中发挥作用。这个基因的突变是导致脑毛细血管畸形的一个原因，这是一种导致癫痫和脑出血的血管畸形。已经识别出多种可变剪接的变异体，它们编码相同的蛋白质。[由RefSeq，2008年7月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
PDCD10 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
